Innovative computational approaches shed light on genetic mechanisms underlying cognitive impairment among children born extremely preterm.

We can see that in the European population, the lead variant rs11829294 in the TEAD4 region has a number of LD tags (e.g., 21 variants with r 2 ≥ 0.8) and some of them had highly significant p values; by contrast, the lead variant rs79453226 in the STX18 region has fewer LD tags (2 variants with r 2 ≥ 0.8) that showed suggestive association (Fig. 3 a).

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