Novel chalcone-derived pyrazoles as potential therapeutic agents for the treatment of non-small cell lung cancer.

3 a,b, treatment of A-549, H226, and H460 cells with PCH-1 after 24 h significantly (**p < 0.001) induced cell cycle arrest in the G 2 /M phase, and this effect was followed by a decreasing trend at 48 h as compared to control.

also in 47,180 other papers

There was an apparent trend showing that the indole part attached to the heptylamine rings had a better score if it was located deeper at the vinblastine binding site of tubulin.

also in 709 other papers