Selected high-degree genes were highly significant as potential biomarkers to predict prognosis in cancer patients than low-degree genes in several cancer types We computed the hazard ratio (HR) of the selected high-degree target genes as the genes targeted by four or more miRNAs and low-degree target genes as the genes targeted by only one miRNA to get the optimized list of high-degree and low-degree genes.
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Computing microRNA-gene interaction networks in pan-cancer using miRDriver.
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