STAT6 Blockade Abrogates <i>Aspergillus</i>-Induced Eosinophilic Chronic Rhinosinusitis and Asthma, A Model of Unified Airway Disease.

RNA sequencing analysis (RNA-seq) of total RNA extracted from mouse sinuses after 12 weeks of fungal challenge revealed numerous highly significant differences in DEGs, including DEGs that were both higher and lower in expression in mice with airway mycosis as compared to vehicle challenged ( Figure 3A and Supplementary Table 2 ).

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