An Orally Bioavailable and Highly Efficacious Inhibitor of CDK9/FLT3 for the Treatment of Acute Myeloid Leukemia.

A slight trend towards an increase in the G 1 population of the MV4-11 cells (16% increment) was noted after incubation with 0.3 μM CDDD11-8 for 24 h ( Figure 2 C).

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