Genetic Variants miR-126, miR-146a, miR-196a2, and miR-499 in Polycystic Ovary Syndrome.

Combining these SNPs in miR-499, mi146a, miR-196a and miR-126 respectively into allele haplotypes found highly significant odds ratios (95% CI) of 0.40 (0.29–0.54) ( p < 0.001) for the C-G-C-G haplotype, and 0.46 (0.30–0.70) ( p = 0.002) for the C-C-C-A haplotype ( p = 0.002) for PCOS.

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