Recently, a decreasing trend of SIRT1 and activated AMPK/PGC-1a protein have been found in PE placentas ( 53 ), and inhibited SIRT1 and PGC-1a have been found in a group of patients with both intrauterine growth restriction and PE ( 54 ).
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Recently, a decreasing trend of SIRT1 and activated AMPK/PGC-1a protein have been found in PE placentas ( 53 ), and inhibited SIRT1 and PGC-1a have been found in a group of patients with both intrauterine growth restriction and PE ( 54 ).