Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria.

In miro1(tm1966); miro-2(tm2933) animals, there is a slight trend of fewer axonal mitochondria but the density is not significantly reduced compared to the control (Figure 1—figure supplement 1B), which is similar to the previous findings in touch receptor neurons (Sure et al., 2018).

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