Significance of chemotherapy-free interval and tumor regression grade in patients with recurrent esophageal squamous cell carcinoma receiving chemotherapy with fluorouracil and platinum after esophagectomy following preoperative chemotherapy.

Esophagus · 2022 · PMC8921032 · PMID 34611830

Europe PMC DOI

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0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

marginal significanceP = 0.055so close (0.05 < p ≤ 0.1)

Impact of CFI and TRG Patients with a CFI < 6 months had shorter PFS with marginal significance (median 1.8 vs. 3,4 months, HR 1.80, 95% CI 0.97–3.34, P = 0.055) and significantly shorter OS (median 7.1 vs. 14.5 months, HR 2.42, 95% CI 1.23–4.77, P = 0.008) compared with those with a CFI ≥ 6 months (Fig. 2 ).

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