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Use of nephrotoxic medications in adults with chronic kidney disease in Swedish and US routine care.

Clin Kidney J · 2022 · PMC8922703 · PMID 35296039

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an increasing trendno p-value reported
The use of most drug classes decreased with lower eGFR categories, with the exception of the proportion of nephrotoxic antibiotics, which showed an increasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.