These three papers reported that a decrease of at least 10% in TBR max early after completion of RCT-TMZ was a highly significant and independent statistical predictor for longer PFS and OS. 20 , 22 , 23 In addition, Galldiks et al. 2012 found a decrease in T vol 6-8 weeks after completing RCT-TMZ to be prognostic of PFS, although Piroth et al. 2013 could not confirm the same relationship.
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A systematic review of amino acid PET in assessing treatment response to temozolomide in glioma.
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