However, the joint influence of cg16936953 and the score was statistically significantly associated with CVD death (p < 0.05), and the adjusted hazard ratio (HR) was marginally statistically significant for cg16936953 [HR 4.38, 95% confidence intervals (CI) 0.79–24.3, p = 0.09] and the score (p = 0.06), respectively.
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Methylation at CpG sites related to growth differentiation factor-15 was not prospectively associated with cardiovascular death in discordant monozygotic twins.
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