Third, when restricting the analysis to patients presenting early (<3 h) from chest pain onset [a population in whom current ESC guidelines do not recommend the use of a hs-cTnT/I-only approach (0 h-sample), but rather the ESC 0/1 h- or ESC 0/2 h-algorithm], a possible trend towards higher sensitivity for the combination of hs-cTnT/I with copeptin vs. the use of hs-cTnT <5 ng/L or hs-TnI <4 ng/L emerged in the Norwegian cohort.
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Adding stress biomarkers to high-sensitivity cardiac troponin for rapid non-ST-elevation myocardial infarction rule-out protocols.
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