Longitudinal study of the mcr-1 gene prevalence in Spanish food-producing pigs from 1998 to 2021 and its relationship with the use of polymyxins.

Porcine Health Manag · 2022 · PMC8932235 · PMID 35300732

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a decreasing trendno p-value reported

Conclusions Our results showed a connection between polymyxin sales and colistin resistance in Spanish pigs for food-production in a range of nine years, and a decreasing trend of colistin resistance ( mcr-1 gene) since the EMA and AEMPS strategies were applied in 2016 to reduce colistin use in animals.

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