A point mutation in HIV-1 integrase redirects proviral integration into centromeric repeats.

Nat Commun · 2022 · PMC8933506 · PMID 35304442

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highly significantno p-value reported

Cumulative data of all libraries yields highly significant differences in integration pattern between the K258R and WT viruses (Table S1 ), but examining individual experiments shows a wide range in the magnitude of the effect (Fig. 3B ).

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