Value of UGT2B7-161 Single Nucleotide Polymorphism in Predicting the Risk of Cardiotoxicity in HER-2 Positive Breast Cancer Patients Who Underwent Pertuzumab Combined with Trastuzumab Therapy by PSL.

13 In this study, conventional two-dimensional echocardiography left ventricular systolic function parameters did not show myocardial impairment, while GWI, GCW, GWE, and GLS showed a decreasing trend compared with their levels before the therapy (P < 0.05).

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