Association of recurrent mutations in BRCA1, BRCA2, RAD51C, PALB2, and CHEK2 with the risk of borderline ovarian tumor.

Hered Cancer Clin Pract · 2022 · PMC8935754 · PMID 35313928

Europe PMC DOI

hedged sentence

0.0400

closest p · 0.8× alpha

0.0400

boldest claim

The sentences

borderline significantp = 0.04actually significant

In that study, the significant association of CHEK2 missense mutation (c.470T>C) with the risk of non-invasive tumors (OR = 1.7, p = 0.005 for ovarian cystadenoma and OR= 2.6, p = 0.002 for BOTs) and borderline significant correlation with low-grade ovarian cancer (OR=2.1, p = 0.04) were reported.

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