Altogether, patients classified as responders ( n = 9) displayed a trend toward significance of increased ex vivo sensitivity (median DSS of 51.8), compared to patients achieving a poor response ( n = 4) (median DSS of 23.4) [minimal response (MR) = 1, stable disease (SD) = 1, progressive disease (PD) = 2] (Fig. 7F ).
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Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically.
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