The Single Nucleotide Polymorphisms of AP1S1 are Associated with Risk of Esophageal Squamous Cell Carcinoma in Chinese Population.

Pharmgenomics Pers Med · 2022 · PMC8938157 · PMID 35321090

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

marginal significanceP=0.054so close (0.05 < p ≤ 0.1)

In the non-smokers, rs77387752 C>T, a marginal significance was observed in the recessive model (P=0.054, adjusted OR=8.060) and in the co-dominant model when compared TT with CC (P=0.054, adjusted OR=8.045), while cigarette smoking is a risky factor in the dominant model (P=0.087, adjusted OR=1.519).

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borderline significanceno p-value reported

So as for haplotype with T in rs77387752, we only identified AP1S1 TATCC, and its OR was not statistically significant which may be due to its low frequency and borderline significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.