In ROC analysis, the AUC of the EPI-CE Score 0.67 (95% CI 0.56–0.77) was superior to PSA 0.54 (95% CI 0.42–0.66, p =0.0926) and both multiparametric risk calculators PCPT 0.59 (95% CI 0.47–0.71, p =0.3066) and ERSPC 0.60 (95% CI 0.49–0.72, p =0.4079), but failed to reach significance at the current cohort size (Fig. 2 A).
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Validation of a CE-IVD, urine exosomal RNA expression assay for risk assessment of prostate cancer prior to biopsy.
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