Remarkably, we found a highly significant enrichment of the DC1 gene signature in Ductal-2 cells of T1D donors, while no other annotated islet cell type revealed such significant and strong enrichment of gene signatures associated with dendritic cell subtypes ( Fig. 4d and Extended Data Fig. 7a ).
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Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes.
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