Barely Significant
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Does prior administration of rtPA influence acute ischemic stroke clot composition? Findings from the analysis of clots retrieved with mechanical thrombectomy from the RESTORE registry.

J Neurol · 2022 · PMC8940807 · PMID 34415423

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Whilst the effect on RBC (mm 2 ) did not quite reach statistical significance, the very clear trend suggests that tPA administration reduces the content of all main components proportionally.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.