Quantitative Metaproteomics and Activity-based Protein Profiling of Patient Fecal Microbiome Identifies Host and Microbial Serine-type Endopeptidase Activity Associated With Ulcerative Colitis.

Mol Cell Proteomics · 2022 · PMC8941213 · PMID 35033677

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highly significantno p-value reported

STRING analysis of significantly enriched UC host proteins yielded 26 edges among 25 nodes and a highly significant protein–protein interaction (PPI) enrichment p -value of 1.84 × 10 −12 at medium confidence (0.400) suggesting a strong association between tested proteins ( Fig. 2 D and Additional File 4 ) ( 72 ).

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