a trend toward significancep = 0.067
For the negative factor, Tukey's post hoc test showed significant differences between the C/C and C/G female carriers ( p < 0.05), C/C and G/G female carriers ( p < 0.05), and C/C and G/G male carriers ( p < 0.05) and a trend toward significance when the males with the C/C and C/G genotypes were compared ( p = 0.067).