The antiproliferative effect was most prominent at a concentration of 120 μg/ml hr-Gal1 and 3 and led to a highly significant reduction to 45% and 65%, respectively, when compared to the positive control ( Fig 3B ).
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Galectin-1 and -3 in high amounts inhibit angiogenic properties of human retinal microvascular endothelial cells in vitro.
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