Barely Significant
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HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway.

Autophagy · 2022 · PMC8942416 · PMID 34024230

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an increasing trendno p-value reported
There was an increasing trend of LC3B, ATG5 and BECN1 at the mRNA level after HG treatment, but there were no statistically significant changes found in ARPE-19 cells (Figure S1A).

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