Decrease in RNase HII and Accumulation of lncRNAs/DNA Hybrids: A Causal Implication in Psoriasis?

With deep-sequencing analysis, we detect signals at the centromeric regions of chromosomes 4, 5, 12, 13, 20, 21, and Y, of all DNA-bound RNA samples with highly significant enriched repeat sequences of CCATT/GGTAA ( Figure 8 ).

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