In Vitro Biological Evaluation of Aprepitant Based ¹⁷⁷Lu-Radioconjugates.

Thus, an interesting trend can be observed for radioconjugates with aliphatic linkers ( Figure 2 ), since initially the affinity for the receptor increases with linker lengthening for radioconjugates with butyl and hexyl linker the affinity is optimal, and then it decreases with further elongation of the aliphatic linker in the molecule.

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