Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells.

BMC Cancer · 2022 · PMC8953069 · PMID 35331184

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an increasing trendno p-value reported

While the death rates from other cancers are decreasing due to advances in diagnosis and therapeutics, the incidence and the mortality of HCC follow an increasing trend due to high rate of obesity associated liver diseases [ 3 , 4 ].

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