highly significantp < 0.001
In an analysis involving only the workers who reported suffering from headaches, a comparison of the 2 genders showed that headache impact on productivity was significantly higher in females ( n = 368; age 46.8 ± 10.7; HIT-6 = 53.3 ± 8.5) than in males ( n = 141, age = 43.7 ± 11.1; HIT-6= 49.6 ± 8.50), The disparity, evaluated by means of the Mann–Whitney U test, was highly significant ( p < 0.001).