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Metabolic Landscape of Bronchoalveolar Lavage Fluid in Coronavirus Disease 2019 at Single Cell Resolution.

Front Immunol · 2022 · PMC8957829 · PMID 35350779

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a decreasing trendno p-value reported
In severe COVID-19 patients, the exhaustion of immune cells resulted in lymphocytopenia and impaired immune functions, and also the overall metabolic activity of immune cells showed a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.