While a nonsignificant trend towards a mortality benefit with Impella was observed in the subgroup of studies with a higher percentage of adoption of higher MCS (RR = 0.94; 95% CI 0.77–1.15; p = 0.529), short-term mortality was significantly lower with IABP in the subgroup of studies with lower adoption of a high MCS (RR = 1.26; 95% CI 1.08–1.48; p = 0.005) (Supplementary Fig. 4).
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Use of Impella device in cardiogenic shock and its clinical outcomes: A systematic review and meta-analysis.
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