Molecularly engineered tumor acidity-responsive plant toxin gelonin for safe and efficient cancer therapy.

Student's t-test was used to perform the statistical analysis for comparison between treatment and control groups, and difference was considered statistically significant when P < 0.05 (*) and highly significant when P < 0.01 (**). 3 Results and discussion 3.1 Biosynthesis and characterization of TpG The expression vector pET32a- pHLIP-Gelonin was constructed and successfully transformed into the competent E. coli DH5α as confirmed by agarose gel electrophoresis ( Fig.

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