IRX4204 Impairs GC Reactions Although the GC B-cell frequency was not significantly different between the groups ( Figures 1E, H ) despite reduced Tfh and increased Tfr and Tfr/Tfh ratio, there was a statistical trend towards smaller GC size in recipients of IRX4204 prophylaxis ( Figures 2A, B ).
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Targeting the Retinoid X Receptor Pathway Prevents and Ameliorates Murine Chronic Graft-Versus-Host Disease.
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