In each BMI category (BMI≤24·0, 24·0–28·0 or ≥28·0 kg/m 2 ), according to the overweight/obesity criteria for China, 32 subjects with higher WC had higher GREM2 levels; whereas, in the subgroup with central obesity, serum GREM2 levels showed a decreasing trend in three BMI categories ( Figure 1 e).
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GREM2 is associated with human central obesity and inhibits visceral preadipocyte browning.
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