Barely Significant
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Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.

Front Cell Infect Microbiol · 2022 · PMC8965314 · PMID 35372122

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a decreasing trendno p-value reported
The observed_species, Shannon, chao1, and ACE index were higher in the CLP group compared to the SC group and showed a decreasing trend after Sivelestat treatment, but the difference was not statistically significant.

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