Accordingly, during the early life stage, the difference in cognitive function between the carriers and non-carriers may not be significant, while as people age, the harmful effects of genetic variants may build up, and the carriers may have a lower average cognitive function compared with non-carriers of the same age due to the cumulative damage on neurons ( Bai and Mei, 2011 ).
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Associations of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Polymorphism With Cognitive Impairment Among the Oldest-Old in China.
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