Efficacy of <i>Brimhana Nasya</i> and <i>Ashwagandha (Withania</i> somnifera <i>(</i>L.) Dunal<i>) root</i> powder in primary insomnia in elderly male: A randomized open-label clinical study.

Results: On subjective sleep quality 86.66% relief with P < 0.0001, on sleep latency 60.02% improvement with P < 0.0001, improvement in sleep duration was reported in 89.15% of patients with P < 0.0001 and improvement in sleep efficiency was reported in 90.14% of patients with statistically extremely significant P < 0.0001 were observed in combined therapy group ( Ksheera Bala Taila Brimhana Nasya along with oral administration of Ashwagandha root powder ) .

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They reported highly significant results in 6 components out of 7 components of PSQI, expect in sleep medication.[ 14 ] Various research studies indicate that lipophilic compounds increase the penetration of the drugs.

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