Neutralization Sensitivity of HIV-1 CRF07_BC From an Untreated Patient With a Focus on Evolution Over Time.

Front Cell Infect Microbiol · 2022 · PMC8968086 · PMID 35372102

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0.0010

closest p · 0.0× alpha

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boldest claim

The sentences

a decreasing trendp < 0.001actually significant

The genetic distance showed a decreasing trend over time (Pearson correlation coefficient r = – 0.509, p < 0.001), suggesting that the sequence diversity of early virus was higher.

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an increasing trendp < 0.01actually significant

By measuring the length of amino acid sequences, it was observed that the amino acid sequence at each time point of V2 and V3 remained stable, whereas the amino acid sequence at each time point of the V4 and V5 regions showed an increasing trend over time, compared with the 201603 time point (p < 0.01).

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