High-Coverage Serum Metabolomics Reveals Metabolic Pathway Dysregulation in Diabetic Retinopathy: A Propensity Score-Matched Study.

Front Mol Biosci · 2022 · PMC8970305 · PMID 35372500

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a decreasing trendno p-value reported

According to module a, most of ω -6 PUFAs, like linoleic acid (LA), γ -linoleic acid (GLA), arachidonic acid (AA), et al., and ω -3 PUFAs, like a -linoleic acid (ALA), docosahexaenoic acid (DHA), eicosapentanoic acid (EPA), et al., expressed a decreasing trend in DR patients while the metabolites of ω -6 PUFAs (12-/15-HETE) were significantly up-regulated.

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