Compared with the number at baseline, the number of IFN-γ + spots generated from CD8 + T cells on day 14 after H101 treatment showed an increasing trend, indicating a tumor-specific immune response is likely activated by H101 ( Figure 4 C).
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Intraperitoneal oncolytic virotherapy for patients with malignant ascites: Characterization of clinical efficacy and antitumor immune response.
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