Can molecular targeting the TNFα-ERK-ETS1-IL27Rα pathway keep us young and healthy by protecting HSCs from aging?

Blood Sci · 2020 · PMC8975103 · PMID 35400025

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highly significantno p-value reported

Therefore, these findings are highly significant by providing the first link between cell-extrinsic and cell-intrinsic communications that lead to HSC aging via the activation of the TNFα-ERK-ETS1-IL27Rα pathway.

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