Barely Significant
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Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically.

Nat Commun · 2022 · PMC8975869 · PMID 35365603

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might be significantno p-value reported
For hydrophobic species, and particularly for environment-sensitive fluorophores, we reasoned that this difference might be significant.

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