A quantitative evaluation revealed a highly significant elevation in the number of cells migrating through the Boyden chamber when the medium in the lower chamber was CM from colorectal cancer cells transfected with edited AZIN1, whereas CM from WT AZIN1 showed no apparent difference, compared to the control group (Fig. 2A ).
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A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer.
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