Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway.

Invest Ophthalmol Vis Sci · 2022 · PMC8976919 · PMID 35353124

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highly significantno p-value reported

26 treated male albino rats with 0.5 mg/kg/d isotretinoin (dissolved in 0.5 mL distilled water) for three months, morphometric analysis of the mean area of the acinar tissue in the isotretinoin-treated group showed a highly significant decrease by high magnification images.

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