Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center.

J Immunother Cancer · 2022 · PMC8977792 · PMID 35365586

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of borderline significanceno p-value reported

Alteration in a Notch pathway gene (three patients) was of borderline significance for association with PFS: patients with an oncogenic or likely oncogenic alteration in this pathway had a median PFS of 7.9 (95% CI 5.1 to not reached) compared with 17.9 weeks in patients without such alteration (10.0 to not reached) (p=0.052).

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