Barely Significant
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Body Mass Index, Interleukin-6 Signaling and Multiple Sclerosis: A Mendelian Randomization Study.

Front Immunol · 2022 · PMC8978959 · PMID 35386698

Europe PMCDOI
1
hedged sentence
0.0460
closest p · 0.9× alpha
0.0460
boldest claim

The sentences

borderline significantp = 0.046actually significant
Likewise, the effect of higher BMI on MS after adjustment for IL-6 signaling remained, though this direct effect is considerably smaller in effect size and only borderline significant compared to the total effect obtained in the univariable analyses without adjustment for IL-6 signaling (MVMR: OR = 1.16, 95% CI =1.00-1.34, p = 0.046) ( Figure 3 ).

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