marginal significanceP = 0.10
Our results about RFI shows that four studies with a marginal significance ( P = 0.10, I 2 = 0%) recorded RFI, which means that UTI treatment could protect renal function in CPB patients, this finding is consistent with a retrospective study [ 52 ]. previous studies [ 53 , 54 ] proved that the systematic inflammatory response syndrome in CPB plays a vital role in the development of RFI, and other studies had found a correlation between UTI treatment and multiple organ function protection [ 55 ].