Barely Significant
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Modifiable psychosocial risk factors and delayed onset of dementia in older populations: analysis of two prospective US cohorts.

BMJ Open · 2022 · PMC8981290 · PMID 35379643

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highly significantno p-value reported
28 While neuroticism has received somewhat less attention as a risk factor for dementia than depressive symptomatology, a recent meta-analysis found highly significant relations of neuroticism to dementia. 8 Across 12 prospective studies, 8 each SD increase in neuroticism score was associated with an incremental increase in dementia risk (pooled HR=1.24, 95% CI 1.15 to 1.33).

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