Immune checkpoint inhibitors and adrenal insufficiency: a large-sample case series study.

Ann Transl Med · 2022 · PMC8987884 · PMID 35402601

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may be significantno p-value reported

Furthermore, in primary AI, there may be significant hyponatremia and hyperkalemia; In secondary AI, low or inappropriately normal TSH levels and low free thyroxine (FT4) levels may also be observed, and enlargement or enhancement of the pituitary region on MRI of the brain may also provide important information for the diagnosis of secondary AI ( 23 ).

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